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Home   COVID-19 treatment studies for Bamlanivimab/etesevimab  COVID-19 treatment studies for Bamlaniv../e..  C19 studies: Bamlaniv../e..  Bamlaniv../e..   Select treatmentSelect treatmentTreatmentsTreatments
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0 0.5 1 1.5 2+ Mortality -119% Improvement Relative Risk Hospitalization 52% Progression 20% c19ly.com Delasobera et al. Bamlaniv../e.. for COVID-19 EARLY Favors bamlanivimab/e.. Favors control
Delasobera, 438 patient bamlanivimab/etesevimab early treatment study: 52% lower hospitalization [p=0.01] and 20% lower progression [p=0.52] https://c19p.org/delasobera
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Impact of Rapidly Deployed COVID-19 Monoclonal Antibody Infusion Clinics on Rate of Hospitalization
Delasobera et al., Infectious Diseases in Clinical Practice, doi:10.1097/IPC.0000000000001109
27 Jan 2022    Source   PDF   Share   Tweet
Retrospective 438 patients in the USA, 253 treated with bamlanivimab, showing significantly lower hospitalization with treatment.
Efficacy is highly variant dependent. Unlikely to be effective for omicron [Liu, Sheward, VanBlargan].
risk of death, 119.4% higher, RR 2.19, p = 0.64, treatment 3 of 253 (1.2%), control 1 of 185 (0.5%).
risk of hospitalization, 52.2% lower, RR 0.48, p = 0.01, treatment 17 of 253 (6.7%), control 26 of 185 (14.1%), NNT 14.
risk of progression, 19.9% lower, RR 0.80, p = 0.52, treatment 23 of 253 (9.1%), control 21 of 185 (11.4%), NNT 44, ER followup visit.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Delasobera et al., 1/27/2022, retrospective, USA, North America, peer-reviewed, 12 authors.
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