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LY-CoV study #5 of 5
1/21 Pre-Exposure Prophylaxis study (treated before exposed to the virus)
Lilly, Press Release (Preprint)
Lilly's neutralizing antibody bamlanivimab (LY-CoV555) prevented COVID-19 at nursing homes in the BLAZE-2 trial, reducing risk by up to 80 percent for residents
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Press release on the BLAZE-2 trial at nursing homes showing significantly lower symptomatic COVID-19 with treatment.

Lilly et al., 1/21/2021, Randomized Controlled Trial, USA, North America, preprint, 1 author.
risk of symptomatic case, 57.0% lower, RR 0.43, p < 0.001, treatment 483, control 482, group sizes estimated because they were not supplied.
risk of symptomatic case, 80.0% lower, RR 0.20, p < 0.001, treatment 150, control 149, nursing home residents, group sizes estimated because they were not supplied.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.
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