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Bamlanivimab study #11   Meta Analysis
11/2 N/A
Kaleta et al., Research Square, doi:10.21203/rs.3.rs-995033/v1 (Preprint)
Antibody escape and global spread of SARS-CoV-2 lineage A.27
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Anaysis of antibody escape showing variant A.27 completely escaped neutralization with LY-COV555 and partially with REGN10987. B.1.617.2 escaped these antibodies in a similar manner, suggesting that L452R facilitates the escape. Authors note that B.1.351 and P.1 escaped LY-COV555 and REGN10933, likely facilitated by the E484K mutation, suggesting that L452R and E484K lead to escape from LY-COV555 and to partial resistance to either REGN10987 or REGN10933, respectively.
Kaleta et al., 11/2/2021, preprint, 33 authors.
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